Jobs: biochemie

Endokrinologický ústav - Národní 8, Praha 1 Oddělení klinické biochemie přijme zdravotního laboranta/laborantku. Více informací o ústavu naleznete na www.endo.cz. • práci na plný úvazek v akreditované laboratoři v centru Prahy v jednosměnném provozu • možnost dalšího profesního rozvoje, specializační vzdělávání • 5...

Revmatologický ústav Provozujeme ústav pro výzkum a léčbu revmatických onemocnění, včetně následné rehabilitace. Poskytujeme komplexní, odbornou a superkonziliární léčebnou péči. Dále provádíme RTG, sonografické a denzitometrické vyšetření. Provozujeme laboratoře, které zahrnují obory klinická biochemie a další. Více...

PhD projectP-Chiral phosphines as asymmetric organocatalystsTutorUllrich JahnGroupUllrich Jahn GroupChemistry of Natural ProductsAbstractRecently we discovered new P-chiral ligand architectures, which were successfully applied as ligands in asymmetric gold catalysis. In general, phosphines are at the same time useful organocatalysts in a number of reactions....

PhD projectStable nitrogen-heterocyclic radicals for the synthesis of calcium ion channel inhibitorsTutorUllrich JahnGroupUllrich Jahn GroupChemistry of Natural ProductsAbstractThe efficient and versatile synthesis of nitrogen-rich scaffolds requires continuous development, given their relevance to medicinal chemistry and chemical biology. In this project,...

PhD projectGlycine alkoxyamines for new bioconjugation methodologiesTutorUllrich JahnGroupUllrich Jahn GroupChemistry of Natural ProductsAbstractWe just accomplished approaches to glycine alkoxyamines, which hold large promise in bioconjugation. With this project the potential of these non-natural amino acid derivatives for approaching new peptide...

Jsme skupina rostlinných molekulárních biologů na CEITEC MU, hledající do našeho týmunového kolegu/novou kolegyni na poziciLaboratorní technik/techničkaKdo jsme?V naší laboratoři se zabýváme výzkumem hormonálních drah u rostlin, stejně jako optimalizací metod pro editaci genomu u rostlin čeledi Brassicaceae. Technik/technička se bude...

Asistent / Asistentka Ústavu lékařské chemie a biochemieAkademická pozice Pracoviště:Lékařská fakulta v Plzni - Ústav lékařské chemie a biochemieMísto výkonu práce:PlzeňMzdová třída:Asistenti na vysokých školách, AP1Mzdové podmínky:Nástupní mzda od Kč do KčKód pracovního místa: AP1-LFPl-ÚLCHB-135Požadavkyvysokoškolské...

Scientific positionIT specialist in Cryogenic electron microscopy core facilityGroupCryogenic Electron Microscopy Tomáš Kouba GroupJob DescriptionIOCB Prague is a world-leading scientific institution dedicated to chemical and biological research. At IOCB, there is a strong emphasis on the translation of results from basic research into applications.The...

PhD projectTailored chelators for selective recovery of critical metalsTutorMiloslav PolášekGroupMiloslav Polášek GroupCoordination ChemistryAbstractCritical raw materials such as rare earth elements and other strategically important metals are indispensable for modern technologies, yet are increasingly difficult to secure in a sustainable manner. This...

PhD projectSelection and optimization of modified XNA aptamersTutorMichal HocekGroupMichal Hocek GroupBioorganic and Medicinal Chemistry of Nucleic AcidsAbstractThe topic of the dissertation will be the enzymatic synthesis of hypermodified xeno-nucleic acids and their use in aptamer selection. It will be necessary to develop enzymatic synthesis of modified...

PhD projectEnzymatic synthesis of modified oligonucleotides on solid supportTutorMichal HocekGroupMichal Hocek GroupBioorganic and Medicinal Chemistry of Nucleic AcidsAbstractThe aim of the thesis will be the development of an efficient enzymatic synthesis of oligonucleotides on solid support. Diverse solid supports and linkers will be tested for attachment...

PhD projectAp4A-capped RNA: A new layer of gene expression regulationTutorHana Macíčková CahováGroupHana Cahová GroupChemical Biology of Nucleic AcidsAbstractThe recent discovery of non-canonical RNA caps, such as NAD and CoA, has fundamentally changed our understanding of the structural and functional diversity of RNA in all types of cells. In our...

PhD projectComputational tools for Raman optical activityTutorPetr BouřGroupPetr Bouř GroupBiomolecular SpectroscopyAbstractRaman optical activity is a dynamically evolving vibrational spectroscopy, suitable, for example, for structural studies of biomolecules. Spectral interpretations are usually based on molecular dynamics and quantum-chemical methods....

PhD projectExploring RNA cap diversity using LC–MS-based sequencingTutorHana Macíčková CahováGroupHana Cahová GroupChemical Biology of Nucleic AcidsAbstractRecent discoveries of non-canonical RNA caps, such as NAD and CoA, have led to a fundamental reassessment of the structural diversity of RNA across all domains of life. In our research group, we...

PhD projectDisplay of sugars and glycans on DNATutorMichal HocekGroupMichal Hocek GroupBioorganic and Medicinal Chemistry of Nucleic AcidsAbstractThe aim of the thesis will be the enzymatic synthesis of DNA bearing diverse sugars or glycans. The project will start with synthesis of diverze sugar- or glycan-linked dNTPs and their enzymatic incorporation into...

Náplň prácePopis Pracovní PoziceNáplní práce bude komplexní celodenní péče o děti ve věku od 1 roku do 3 let.PožadujemePodmínkou je kladný vztah k dětem, trpělivost a UKONČENÉ vzdělání v níže uvedených oborech:Praktická sestra, všeobecná sestra, dětská sestra, porodní asistentka, zdravotně-sociální pracovník, zdravotnický...

PhD projectPhotogearing at the molecular scale: Mechanistic principles for converting Brownian motion into directed rotationTutorJiří KaletaGroupJiří Kaleta GroupMolecular DevicesAbstractThe dissertation will focus on the mechanistic principles underlying photogearing at the molecular scale, i.e. the conversion of a light-driven primary motion into a...

PhD projectEnantioselective transition metal catalysis using helically chiral ligandsTutorIvo StarýGroupIvo Starý GroupChemistry of Functional MoleculesAbstractAs part of the doctoral project, a new class of helically chiral metal complexes for enantioselective catalysis will be developed. The main part of the work will focus on their design and synthesis....

PhD projectCatalytic synthesis of bioactive atropisomers by aromatic substitutionTutorPaulo De Souza PaiotiGroupPaulo Paioti‬ GroupCatalytic Synthesis of Bioactive MoleculesAbstractOur group recently developed nucleophilic aromatic substitutions for synthesis of drug-like atropisomers, chiral conformational isomers originating from restricted single bond...

PhD projectSpin interactions and multiplicity as a tool for reactivity controlTutorTomáš SlaninaGroupTomáš Slanina GroupRedox PhotochemistryAbstractThe multiplicity of excited states in organic photochemistry is governed by electron spin and its interactions. Excited molecules most commonly occur in singlet or triplet states; interconversion between them...