Cheminformatics Intern

Job Requirements

We're looking for students of Czech Universities, who are interested in a long-term collaboration with MSD.

Have you always wanted to work in a company where your work can have a real impact? Do you enjoy working in an international environment with lots of space for personal development? Are you ready to join a company where we cherish Diversity and Inclusion and the wellbeing of our employees?

Our IT team operates as a business partner, suggesting ideas and innovative solutions that enhance our organizational capabilities. We work collaboratively on an international scale to deliver services and solutions that increase productivity and foster innovation.

Interning as a Data Analyst you will:

We are looking for an organized and detail-oriented student to join our Cheminformatics team as a Chemical Registration Intern. This role is a unique opportunity for a candidate with a strong foundation in chemistry to work at the critical intersection of science and information technology. You will be responsible for ensuring the accuracy and integrity of our company's most valuable asset: our corporate chemical compound database.

The intern will act as a key liaison, working closely with our internal scientists and external Contract Research Organizations (CROs) to process and validate bulk chemical registration requests, with a particular focus on the correct representation of complex molecular structures and stereochemistry.

Key Responsibilities

• Process and manage incoming compound registration requests submitted by medicinal chemists and CRO partners.
• Utilize our proprietary in-house chemical registry system to accurately enter and validate new molecular entities.
• Rigorously review submitted chemical structures for correctness, including proper atom valency, charge, and isotopic labeling.
• Apply your deep understanding of stereochemistry to ensure the correct digital representation of enantiomers, diastereomers, and geometric isomers (e.g., absolute (R/S) and relative (E/Z) configurations).
• Apply your knowledge of stereo configurations and mixture of stereoisomers, stereochemistry labelling, geometric isomerism, Fischer and Haworth projection for monosaccharides, cyclic sugars, amino acids and anomers.
• Use of molecular fingerprints and descriptors for similarity searching as well as conversion between representations.
• Identify and troubleshoot registration errors, communicating effectively with submitting scientists to resolve any structural discrepancies or ambiguities.
• Assist in maintaining the overall quality, consistency, and integrity of the corporate chemical database.
• Contribute to the improvement of registration workflows and documentation.

What should you know / have:

• Strong academic record with completed coursework in organic and physical, analytical chemistry.
• Deep theoretical understanding of chemical structures, IUPAC nomenclature, and advanced stereochemical concepts.
• Proficiency with chemical drawing software (e.g., ChemDraw, MarvinSketch).
• Exceptional attention to detail and a methodical approach to problem-solving.
• Excellent written and verbal communication skills for collaborating with a diverse scientific community.

Preferred:

• Familiarity with chemical databases, compound registration principles, or data management.
• Knowledge of chemical structure representation formats (e.g., MOL, SDF, SMILES,InChL, CAS Registry Numbers).
• Experience with data analysis or scripting (e.g., Python, SQL) is a plus.

Besides a great atmosphere and flexible working environment, we also offer:

• Hourly wage
• Multinational environment in the leading pharma corporation
• Meal vouchers and Multisport card
• Development program (every month trainings, workshops, networking events, etc.)
• Flexible working hours
• Friendly working environment
• Possibility of challenging career

Who we are …

We are known as Merck & Co., Inc., Rahway, New Jersey, USA in the United States and Canada and MSD everywhere else. For more than a century, we have been inventing for life, bringing forward medicines and vaccines for many of the world's most challenging diseases. Today, our company continues to be at the forefront of research to deliver innovative health solutions and advance the prevention and treatment of diseases that threaten people and animals around the world.

What we look for …

In a world of rapid innovation, we seek brave Inventors who want to make an Impact in all aspects of our business, enabling breakthroughs that will affect generations to come. We encourage you to bring your disruptive thinking, collaborative spirit and diverse perspective to our organization. Together we will continue Inventing For Life, Impacting Lives while Inspiring Your Career Growth.

Invent. Impact. Inspire.

We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another's thinking and approach problems collectively. We are an equal opportunity employer, committed to fostering an inclusive and diverse workplace.

Please note our third party recruitment partner, will retain and employ successful applicants for this program.

Search Firm Representatives Please Read Carefully:

Our company does not accept unsolicited assistance from search firms or recruitment agencies for this employment opportunity. Please, no phone calls or emails. All resumes submitted by search firms to any of our employees via email, the Internet or in any form without a valid written search agreement in place for this position will be deemed the sole property of our Company. No fee will be paid in the event the candidate is hired by our Company as a result of the referral or through other means.)

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Requisition ID:P-100928