Clinical Site Manager

1 week ago


Prague, Hlavní město Praha, Czech Republic ICON plc Full time
Clinical Site Manager

ICON plc is a world-leading healthcare intelligence and clinical research organization. We're proud to foster an inclusive environment driving innovation and excellence, and we welcome you to join us on our mission to shape the future of clinical development

We are currently seeking a Senior Clinical Research Associate (CRA) to join our diverse and dynamic team. As a Senior CRA at ICON Plc, you will play a critical role in overseeing and managing clinical trial activities to ensure they are conducted according to protocol, regulatory requirements, and industry standards. You will contribute to the success of clinical trials by ensuring data integrity, participant safety, and compliance throughout the study lifecycle.

What You Will Be Doing:

  • Monitoring clinical trial sites to ensure adherence to study protocols, regulatory requirements, and Good Clinical Practice (GCP) standards.
  • Conducting site visits to assess site performance, resolve issues, and provide support to ensure successful trial execution.
  • Collaborating with cross-functional teams to ensure timely and accurate data collection and reporting.
  • Providing training and guidance to site staff and other CRAs to maintain high standards of clinical trial conduct.
  • Building and maintaining effective relationships with site personnel and stakeholders to facilitate smooth trial operations.

Your Profile:

  • Advanced degree in a relevant field such as life sciences, nursing, or medicine.
  • Extensive experience as a Clinical Research Associate, with a strong understanding of clinical trial processes and regulatory requirements.
  • Proven ability to manage multiple sites and projects simultaneously, with strong organizational and problem-solving skills.
  • Expertise in monitoring practices, data integrity, and site management, with proficiency in relevant clinical trial software and tools.
  • Excellent communication, interpersonal, and stakeholder management skills, with the ability to influence and drive compliance within a complex environment.
  • Ability to travel at least 60% of the time (international and domestic - fly and drive) and should possess a valid driver's license

#LI-AG1

What ICON can offer you:

Our success depends on the quality of our people. That's why we've made it a priority to build a diverse culture that rewards high performance and nurtures talent.

In addition to your competitive salary, ICON offers a range of additional benefits. Our benefits are designed to be competitive within each country and are focused on well-being and work life balance opportunities for you and your family.

Our benefits examples include:

  • Various annual leave entitlements

  • A range of health insurance offerings to suit you and your family's needs.

  • Competitive retirement planning offerings to maximize savings and plan with confidence for the years ahead.

  • Global Employee Assistance Programme, TELUS Health, offering 24-hour access to a global network of over 80,000 independent specialised professionals who are there to support you and your family's well-being.

  • Life assurance

  • Flexible country-specific optional benefits, including childcare vouchers, bike purchase schemes, discounted gym memberships, subsidised travel passes, health assessments, among others.

Visit our careers site to read more about the benefits ICON offers.

At ICON, inclusion & belonging are fundamental to our culture and values.   We're dedicated to providing an inclusive and accessible environment for all candidates. ICON is committed to providing a workplace free of discrimination and harassment. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.

If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please let us know or submit a request here.

Interested in the role, but unsure if you meet all of the requirements? We would encourage you to apply regardless – there's every chance you're exactly what we're looking for here at ICON whether it is for this or other roles.

Are you a current ICON Employee? Please click here to apply



  • Prague, Hlavní město Praha, Czech Republic PSI CRO Full time

    Company DescriptionMilestone One is a Site Enabling Services organization with global headquarters in Zug, Switzerland. We understand what clinical study sites need and our overall mission is to support sites in stronger study delivery.Job DescriptionThe Milestone One Site Coordinator role supports a Clinical Study Site in clinical trial related activities...


  • Prague, Hlavní město Praha, Czech Republic Johnson & Johnson Full time

    At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across...


  • Prague, Hlavní město Praha, Czech Republic Johnson & Johnson Innovative Medicine Full time

    At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to...


  • Prague, Hlavní město Praha, Czech Republic Amgen Full time

    Career CategoryClinicalJob DescriptionResponsible for: •Support Clinical Study Teams by creating of pricing proposals for clinical study budgets and related agreements •Development and periodic monitoring of study level budget estimates •Budget strategy and design including fair market value negotiation guidelines •Payment system configuration...


  • Prague, Hlavní město Praha, Czech Republic Envista Holdings Corporation Full time

    Job Description:Clinical Research Associate plans, implements and manages clinical trials and influences study design and interprets results. Defines clinical trial protocols, standard operating procedures (SOPs) and case report forms (CRFs) for use in clinical trials operations primarily in EU for Kerr Dental products.Job Requirements:The Clinical Research...


  • Prague, Hlavní město Praha, Czech Republic Envista Holdings Full time

    Operating Company: KerrLocation: Prague,Hlavni Mesto Praha,CZDate Posted: December 9, 2025Req Number: R5024786Job Description:Clinical Research Associate plans, implements and manages clinical trials and influences study design and interprets results. Defines clinical trial protocols, standard operating procedures (SOPs) and case report forms (CRFs) for use...


  • Prague, Hlavní město Praha, Czech Republic Novartis Full time

    Job Description SummaryThe Associate Clinical Sourcing Manager supports Novartis clinical trials by managing sourcing activities for Contract Research Organisations (CROs). Ensure compliant, timely, and cost-effective external service delivery to enable the Novartis drug development pipeline.Job DescriptionKey ResponsibilitiesPrepare and release RFI, RFP,...


  • Prague, Hlavní město Praha, Czech Republic IQVIA Full time

    As Local Trial Manager you will be responsible for running international/global studies in all therapeutic areas, managing the operational aspects of projects to meet contractual requirements . You will act as primary point of contact in CZ Republic to lead, manage and co-ordinate the conduct of clinical trials from study start-up (COLA) to close out at a...


  • Prague, Hlavní město Praha, Czech Republic Parexel Full time

    When our values align, there's no limit to what we can achieve. At Parexel, we all share the same goal - to improve the world's health. From clinical trials to regulatory, consulting, and market access, every clinical development solution we provide is underpinned by something special - a deep conviction in what we do.Each of us, no matter what we do at...

  • Site People Manager

    1 week ago


    Prague, Hlavní město Praha, Czech Republic DP World Full time

    At DP World, we enable smarter trade to make a better future for everyone. As we expand our footprint in Central Europe, we are looking for a dynamic Site HR Manager HR function in Ostrava, Czech Republic. This is a pivotal generalist role, acting as the first point of contact for employees and business leaders, ensuring compliance, driving people strategy,...