Technical Product Manager HPC

1 week ago


Prague, Hlavní město Praha, Czech Republic MSD Full time 80,000 - 150,000 per year

Job Description

The Position

We are seeking a seasoned Technical Product Manager with deep expertise in High-Performance Computing (HPC) to lead the development of cutting-edge HPC solutions tailored for Bio-Pharma research. This role demands a strong techno-scientific background combined with proven leadership and people management skills. You will drive the delivery of scalable, high-impact HPC products that accelerate scientific discovery, leveraging AWS compute and storage technologies to meet and exceed client needs. Your ability to communicate complex technical concepts clearly and manage cross-functional teams will be critical to our success.

What will you do?

  • Define and drive the vision, strategy, and roadmap for HPC products that support Bio-Pharma research workflows, ensuring alignment with scientific goals and business objectives.
  • Collaborate closely with research scientists, engineers, and stakeholders to gather requirements, prioritize features, and translate complex computational needs into clear product specifications.
  • Own the end-to-end product lifecycle, from ideation through delivery, ensuring scalable, reliable, and cost-effective HPC solutions leveraging AWS and hybrid cloud environments.
  • Present product strategies, progress, and outcomes to executive leadership and cross-functional teams, fostering transparency and alignment.
  • Lead and coordinate cross-functional teams including HPC engineers, cloud specialists to deliver high-impact HPC products on schedule and within scope.
  • Mentor and support team members' professional growth, fostering a culture of innovation, collaboration, and continuous improvement.
  • Partner with enterprise architecture and engineering leadership to ensure technical feasibility, quality standards, and best practices are integrated into product development.
  • Act as the primary liaison between technical teams and research stakeholders, ensuring clear communication of product capabilities, timelines, and trade-offs.
  • Facilitate agile product development processes including sprint planning, backlog prioritization, and iterative feedback loops to continuously refine HPC solutions.
  • Manage expectations and negotiate priorities among diverse stakeholders, balancing scientific innovation with operational constraints.
  • Monitor product performance, usage metrics, and customer feedback to drive data-informed decisions and continuous product enhancements.
  • Collaborate with finance and engineering teams to manage budgets, optimize cloud resource allocation, and ensure cost-effective HPC operations.
  • Lead capacity planning and technology evaluation to anticipate future research demands and incorporate emerging HPC technologies.
  • Stay abreast of advancements in HPC, cloud computing, AI/ML, and scientific research tools to identify opportunities for product innovation.
  • Champion adoption of new technologies and methodologies that enhance product capabilities and user experience in scientific computing environments.

Qualifications, Skills & Experience Required

  • Bachelor's degree in computer science, Engineering, or a related field; master's degree preferred
  • Proven experience (5+ years) in technical product management or leadership roles within HPC, cloud computing, or scientific research domains
  • Strong technical background with understanding of HPC architectures, cloud platforms (especially AWS), and scientific computing workflows
  • Demonstrated ability to lead cross-functional teams, manage complex projects, and deliver scalable technical products
  • Excellent communication skills, capable of bridging technical and non-technical audiences
  • Experience with agile methodologies and product lifecycle management
  • Strong analytical skills to assess product performance, user needs, and market trends

Nice to have

  • Familiarity with scientific HPC applications (e.g., Gaussian, Grace) and container technologies (Singularity, Apptainer)
  • Experience with GPU-enabled HPC clusters and AI/ML workloads in research contexts
  • Knowledge of HPC job schedulers (PBS, Slurm) and workflow management tools (Nextflow)
  • AWS certifications (Solutions Architect, HPC Specialty) or equivalent cloud credentials
  • Experience managing cloud budgets and optimizing resource allocation for HPC infrastructure

What we offer

  • Exciting work in a great team, global projects, international environment 
  • Opportunity to learn and grow professionally within the company globally 
  • Hybrid working model, flexible role pattern (e.g., even 80% full-time is possible in justified cases) 
  • Pension and health insurance contributions 
  • Internal reward system plus referral programme 
  • 5 weeks annual leave, 5 sick days, 15 days of certified sick leave paid above statutory requirements annually, 40 paid hours annually for volunteering activities, 12 weeks of parental contribution 
  • Cafeteria for tax free benefits according to your choice (meal vouchers, Lítačka, sport, culture, health, travel, etc.), Multisport Card 
  • Vodafone, Raiffeisen Bank, Foodora, and discount programmes 
  • Up-to-date laptop and iPhone 
  • Parking in the garage, showers, refreshments, massage chairs, library, music corner 
  • Competitive salary, incentive pay, and many more 

Ready to take up the challenge? Apply now 
Know anybody who might be interested? Refer this job

Current Employees apply HERE

Current Contingent Workers apply HERE

Search Firm Representatives Please Read Carefully 
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company.  No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails. 

Employee Status:

Regular

Relocation:

VISA Sponsorship:

Travel Requirements:

Flexible Work Arrangements:

Hybrid

Shift:

Valid Driving License:

Hazardous Material(s):


Required Skills:

Agile Application Development, Agile Application Development, Agile Methodology, Amazon Web Services (AWS), Availability Management, Business, Capacity Management, Change Controls, Cloud Engineering, Cloud Services Management, Computational Chemistry, Design Applications, High Performance Computing (HPC), Incident Management, Information Management, Information Technology (IT) Infrastructure, IT Service Management (ITSM), Management Process, Product Management, Product Strategies, Release Management, Scientific Software Development, Slurm Workload Manager, Software Development, Software Development Life Cycle (SDLC) {+ 5 more}

Preferred Skills:

Job Posting End Date:

09/29/2025

*A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

Requisition ID:R350535



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